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The body monitors the levels of oxygen in the blood to regulate breathing. Isabel is running in a marathon and is near the finish line. She feels out of breath. How will her nervous system work to generate a reaction? Arrange the tiles in chronological order.

Sensory neurons generate an impulse.
Isabel's breathing rate increases.
The central nervous system relays an
impulse to certain brain regions.
The brain sends signals through
motor neurons.
Sensory receptors in the arteries
detect low oxygen levels.