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In a patient with type 2 diabetes exhibiting worsening glycosuria and ketonuria after starting metformin and canagliflozin, what is the most appropriate clinical action? a. Increase the dose of canagliflozin. b. Switch from metformin to another oral hypoglycemic agent. c. Reassure that worsening glycosuria is expected and not a concern. d. Admit to the hospital for suspected diabetic ketoacidosis (DKA) and start insulin therapy. e. Continue the same medication as the blood glucose correction is a sign of clinical improvement.
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