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Why is metformin not useful in patients with type 1 DM (IDDM)? - Because IDDM can only be treated with desmopressin - It increases insulin sensitivity, which is not pathologically low in IDDM - It reduces the synthesis of new glucose in the liver, but patients with IDDM often have liver failure so effects on the liver need to be avoided - It decreases blood sugar levels, which are not abnormally high in patients with untreated IDDM
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