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Draw the structure(s) of the major organic product(s) of the following reaction. 1. lithium diisopropylamide / hexane 2. 1 eq. CH3I You do not have to consider stereochemistry. Omit products derived from the acidic or basic reagent itself, e.g. HN(i-Pr)2 derived from N(i-Pr)2-. If no reaction occurs, draw the organic starting material. If substantial starting material is present at the end of the reaction, include it in the products. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate structures with signs from the drop-down menu.

Sagot :

Answer:

See explanation below

Explanation:

You are not providing the starting material, however, I manage to find a similar question to this, so I'm gonna use it as a basis to help you answer yours.

Now let's analyze what is happening in the reaction so we can predict the final product.

We have a ketone here, reacting at first with LDA. This is a very strong base that is commonly used in reactions with ketones and aldehydes to promove a condensation. To do this, as LDA is a strong base it will occur firts an acid base reaction, substracting the most acidic hydrogen in the molecule (Which in this case, is the Beta hydrogen of the carbonile). This will cause an enolate formation.

Then, this enolate will react with the CH3I and form a new product. The final result would be a ketone with a methyl group now attached. In the picture 2, you have the mechanism and final product.

Hope this helps

View image Joetheelite
View image Joetheelite
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