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Answer:
Paying debt, enforcing federal laws and interference of Spain and Britain in US internal affairs.
Explanation:
The main challenge faced by George Washington as the first president was the paying of debt which was taken by the United States from other countries in order to support its economy. Enforcing of federal laws across the country is another challenge because people did not want any federal law which was imposed on them. The solving of issues with Spain and Britain is also a big challenge for George Washington.