IDNLearn.com: Where questions are met with accurate and insightful answers. Our experts provide accurate and detailed responses to help you navigate any topic or issue with confidence.
Sagot :
Answer:
Fed state - Insulin; dephosphorylation; increase; glycolysis
Fasting state - Glucagon; phosphorylation; decrease; gluconeogenesis
Explanation:
Fructose-2,6-bisphosphate is an allosteric regulator of the enzymes phosphofructokinase-1 and fructose1,6-bisphosphatase-1 which are involved in glycolysis and gluconeogenesis respectively.
After a meal the body is in a fed state, which stimulates the pancreas to secrete the hormone insulin . The plasma membrane receptor on the liver binds to this hormone and activates a signaling pathway that results in the dephosphorylation of the bifunctional enzyme, phosphofructokinase-2/fructose-2,6-bisphosphatase. This event causes a(n) increase in the concentration level of the fructose-2,6-bisphosphate (F-2,6-BP). This new concentration of F-2,6-BP activates the glycolysis pathway.
In a fasting state, the pancreas secretes the hormone glucagon . The plasma membrane receptor on the liver binds to this hormone and activates a signaling pathway that results in the phosphorylation of the bifunctional enzyme phosphofructokinase-2/fructose-2,6-bisphosphatase. This event causes a(n) decrease in the concentration level of F-2,6-BP. This new concentration level of F-2,6-BP. activates the gluconeogenesis pathway, by allowing inhibition of the reciprocal reaction.

Thank you for being part of this discussion. Keep exploring, asking questions, and sharing your insights with the community. Together, we can find the best solutions. Find reliable answers at IDNLearn.com. Thanks for stopping by, and come back for more trustworthy solutions.