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Which of the following statements explains how N-formylmethionine (fMet) is only associated with the 5' AUG initiation codon and not with internal AUG codons, given that methionine in both cases in encoded by an AUG in the mRNA. Select all that apply. Group of answer choices Only fMet-tRNA(fMet) can bind first to the P site in the ribosome. There are more than one tRNA with the 5' CAU 3' anticodon. fMet is always incorporated at interior AUG sites and then deformylated after translation. The N-formyl group attached to methionine prevents fMet from entering interior positions in a polypeptide.

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Answer:

  • Only fMet-tRNA(fMet) can bind first to the P site in the ribosome. ( A )
  • There are more than one tRNA with the 5' CAU 3' anticodon. ( B )
  • The N-formyl group attached to methionine prevents fMet from entering  interior positions in a polypeptide. ( D )

Explanation:

The statements that explains how N--formyl methionine (fMet) is only associated with the 5' AUG initiation codon and not with internal AUG codons, given that methionine in both cases in encoded by an AUG in the mRNA are :

Only fMet-tRNA(fMet) can bind first to the P site in the ribosome. ( A )

There are more than one tRNA with the 5' CAU 3' anticodon. ( B )

The N-formyl group attached to methionine prevents fMet from entering  interior positions in a polypeptide. ( D )

While statement C is wrong.

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