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C. Growth hormone promotes the closure of the epiphyseal plate.
The closure of the epiphyseal plate is NOT an effect of growth hormone (option c).
The epiphyseal plate is a layer of hyaline cartilage between the epiphyses and metaphyses at the ends of long bones.
The epiphyseal plate is completely closed when bone growth is completed (around age 18 to 21 years).
Different hormones (i.e., testosterone and estrogen) released at puberty initiate the closure of epiphyseal plates.
In conclusion, the closure of the epiphyseal plate is NOT an effect of growth hormone (option c).
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