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Answer:
The correct option is this: MIX THE BLOOD IN A HYPOTONIC SOLUTION WHICH WILL CAUSE THE RED BLOOD CELL TO LYSE.
In order to reduce interference from red blood cell, mix the blood sample with a hypotonic solution. Because the red blood cells has more solute concentration, water from the hypotonic solution will enter into its cells and with time the cells will burst since they do not have much resistance against lysis. The bursting of the cells will eliminate the red blood cells and leave you with white blood cell to work with.