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The uric acid cycle is a cyclic adaptation of the process used for mammalian purine catabolism. Inosine monophosphate (IMP) is formed which reacts with pyrophosphate to form hypoxanthine and 5-phosphoribosylpyrophosphate (PRPP). This reaction is catalysed by hypoxanthine phosphoribosyltransferase (EC 2.4.
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