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Sagot :
In relation to the situation described in the question, I would not agree with the student's assessment that the new cell line would be fine for the experiment given that the main goal of the experiment was to make conclusions about testosterone-specific pathways.
The student in question wishes to create an experiment to test the effect of testosterone in a specific signal transduction pathway. The initial experiment designed by the student was correct as it takes the cell line as a control variable to measure the pathway effects.
However, Once the student changed the cell line, he affected the accuracy of the experiment since hormones such as testosterone behave differently in the absence of specific pathways and will be more affected by competetive hormones amongst those new pathways.
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