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(c) Based on the data, identify the drug that, from the ART-S strain to the ART-R strain, has the largest relative increase in the IC50. Based on the information



provided about the mouse model, calculate how many times more sensitive the original ART-S Plasmodium strain is to artesunate than is the ART-R strain


Sagot :

Based on drug potency, the IC50 level of ART-S strain is much lower than the ART-R strain.

What is IC50?

IC50 is the half maximun inbitory concentration of a substance.

It is a measure of the potency of a drug or substance in inhibiting a specific biological or biochemical function.

The lower the IC50 value, the more potent the drug or substance is.

ART-S strain and ART-R strain refers to strains of Plasmodium that are sensitive and resistant respectively to artesunate treatment.

Therefore, the IC50 level of ART-S strain is much lower than the ART-R strain.

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