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A mother has hemophilia, and the father is unaffected. What is the probability that their son will have hemophilia? Their daughter?

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Answer:

A 25% (one in four) chance of having a son with hemophilia. A 25% chance of having a son with normal blood clotting. A 25% chance of having a daughter who is a carrier. A 25% chance of having a daughter who has hemophilia.

Explanation:

In the extremely rare event that both the mother and the father have the affected X chromosomes then there is a 50% chance that their sons will be born with hemophilia. There will be a 50% chance their daughters will be carriers and a 50% chance they will also have the condition.

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