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From anecdotes he heard, Edward Jenner came up with the premise and conclusion that dairy maids could not get small pox because they had previously been exposed to the virus.
He also came to the conclusion that small pox may be passed from one person to the next. Edward Jenner came to this conclusion based on stories he had heard about dairy maids being immune to smallpox.
In 1736, Edward Jenner met Sarah Nelms, a young dairy girl with small pox lesions. Edward Jenner then vaccinated an 8-year-old kid named James Phipps with material from Nelms' small pox lesion. James Phipps suffered a fever and became unwell, but he recovered completely after ten days.
Jenner infected the same boy with materials from a fresh small pox lesion a month later. There was no sickness in the boy.
When Edward Jenner was inoculated/vaccinated with matter from a small pox lesion, he came to the conclusion that he could acquire total protection from small pox.
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