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Metformin-associated lactic acidosis (MALA)
Metformin prevents lactic acid from being oxidized in the mitochondria, which can result in lactic acidosis, a medical emergency with a 50% mortality rate. Fortunately, lactic acidosis is uncommon in people who take metformin at the prescribed doses and have healthy kidney function.
What is type 2 diabetes mellitus?
A disorder in the body's ability to control and utilize sugar (glucose) as fuel is type 2 diabetes. This chronic (long-term) disorder causes the bloodstream to circulate with an excessive amount of sugar. Over time, cardiovascular, neurological, and immune system issues might result from excessive blood sugar levels.
Cells respond poorly to insulin and take in less sugar when the pancreas does not create enough of this hormone, which controls the flow of sugar into your cells.
Metformin is an oral diabetes medication that aids in blood sugar regulation. Consequently, since it lowers hepatic glycogenolysis, is a top medication choice for treating hyperglycemia in type 2 diabetes mellitus.
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