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Neural control of gfr is mediated by ________ that innervate ________ receptors on vascular smooth muscle causing ________

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Neural control of GFR is mediated by Sympathetic neurons that innervate alpha receptors on vascular smooth muscle causing Vasoconstriction.

How is GFR regulated?

  • The sympathetic division of the nervous system regulates the GFR or Glomerular Filtration Rate.
  • GFR is the sum total of filtration rates of all the working nephrons in the kidney.
  • Sympathetic division comes into action when the mean arterial pressure is very low (below 80mmHg).
  • In response to low blood pressure, the medulla releases norepinephrine through sympathetic nerves.
  • Norepinephrine leads to activation of alpha receptors on arteries which cause vasoconstriction.
  • Alpha receptors are more abundant on afferent arterioles.
  • This leads to vasoconstriction (narrowing) of arteries supplying to the glomerulus.
  • This decreases blood flow to glomerulus, leading to decrease in GFR.

Learn more about Glomerular Filtration Rate here:

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