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Drugs that have anti-inflammatory, analgesic, and antipyretic activities include COX-2 inhibitors (NSAIDs), Ibuprofen and Aspirin.
Anti-inflammatory, analgesic, and antipyretic drugs are a heterogeneous group of compounds, often chemically unrelated (although most of them are organic acids), but nonetheless share certain therapeutic benefits and side effects. The prototype is aspirin.
All aspirin-like drugs are antipyretic, analgesic, and anti-inflammatory, but there are important differences in their effectiveness. For example, paracetamol has antipyretic and analgesic effects, but only weak anti-inflammatory effects. Variations in enzyme sensitivity in target tissues can be important. Aspirin drugs do not alter the perception of sensory modalities other than pain.
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