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Subgingival plaque biofilm phase of periodontal disease progression does the coronal-most portion of the junctional epithelium first detach from the tooth surface.
Numerous diverse ecosystems within the human body offer a unique environment for invading microorganisms. One example of a microniche is the periodontal pocket. As a result of the junctional epithelium's lack of differentiation and attachment to the tooth root, polymorphonuclear leukocytes can move into the periodontal pocket, tend to be colonised with a biofilm of microorganisms.
Actinomyces species and streptococci are the leading early colonists of the subgingival plaque biofilms. The secondary colonisers are typically the more pathogenic species, including Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans.
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