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A trna with the anticodon sequence 5′ iua 3′ will not normally exist because 5′ UAA 3′ is a stop codon.
There are three stop/termination codons UAA, UAG, and UGA.
A unique type of RNA molecule is called a transfer RNA (tRNA). Matching an mRNA codon to the amino acid it codes for is its responsibility. Anticodon is a set of three nucleotides found in each tRNA. One or more distinct mRNA codons can bind to the anticodon of a particular tRNA. The amino acid encoded by the codons to which the tRNA binds is carried by the tRNA molecule as well.
At the third position of the codon, atypical base pairs—between nucleotides other than A-U and G-C—can develop. This phenomenon is referred to as wobble.
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