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Succinate dehydrogenase is the citric acid cycle considered part of aerobic metabolism even though oxygen does not appear.
The respiratory complex II, also known as succinate dehydrogenase (SDH), succinate-coenzyme Q reductase (SQR), or SDH, is an enzyme complex that is present in the inner mitochondrial membrane of eukaryotic and numerous bacterial cells. SDH converts succinate to fumarate as part of the citric acid cycle. SDH shares structural similarities with fumarate reductase, an enzyme that catalyzes the reverse process during anaerobic respiration in bacteria. (1997, Hagerhall). Succinic semialdehyde dehydrogenase impairment is brought on by ALDH5A1 gene mutations. Instructions for creating the succinic semialdehyde dehydrogenase enzyme are found in the ALDH5A1 gene.
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