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The conventional methods for amino acid profiling with tandem mass spectrometry made use of 102 Da neutral loss scan. What does this mean?
A. The first mass analyser selects all fragment ions that weigh 102 Da less than the product ions in the second mass analyser
B. The second mass analyser selects all fragment ions form the collision cell with a weight of 102 Da
C. The second mass analyser selects all fragment ions that weigh 102 Da less than the precursor ion that passed through the first mass analyser
D. The first mass analyser selects all precursor ions that have a m/z value of 102

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Based on the method of neutral loss scan, the correct answer is:

  • The first mass analyzer selects all precursor ions that have a m/z value of 102; option D

What is a neutral loss scan in mass spectrometry?

In tandem mass spectrometry or GC-MS/MS, neutral loss scan is a measuring mode that is used to study compounds showing a common neutral molecule loss during collision-induced dissociation (CID).

In measurements using neutral loss scan, fragments lost as neutral molecules are recorded in Da neutral loss scan values.

Some applications of mass spectrometry is in:

  • identification and characterization drug metabolites
  • authentication and profiling of chemical compounds
  • substructure analysis of unknown components
  • quantification of analytes in biological samples

In conclusion, neutral loss scan is a mode of measurement in tandem spectrometry.

Learn more about mass spectrometry at: https://brainly.com/question/24127899

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