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By notifying the parents that birth defects were not genetic, the attending physician most presumably misdiagnosed the very first child's smith-lemli-opitz syndrome.
What exactly is the Smith-Lemli-Opitz syndrome?
Smith-Lemli-Opitz syndrome is a neurocognitive disorder that affects several body systems.
This disorder is distinguished by distinctive facial characteristics, a limited brain size (microcephaly), cognitive impairment as well as learning disabilities, and behavioral difficulties.
In the given circumstance;
- Given the birth of a second baby of Smith-Lemli-Opitz disorder, both parents have been most expected carriers for the syndrome's recessive gene.
- In that case, each of their children has a 25% chance of being affected.
Thus, the chance of having two affected children from heterozygous parents is 0.25 × 0.25 = 0.0625, or a little more than 6%.
To know more about genetic disorders, here
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