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Being a carrier of, or having sickle cell anemia is adaptive in this region, because it protects against malaria. Subsequently, children born with sickle cell anemia are less likely to die from malaria.
A parasite that frequently infects a particular kind of mosquito that feeds on people can result in the severe and occasionally deadly illness known as malaria. Malaria often causes severe disease, including high fevers, shivering chills, and flu-like symptoms. Humans are infected by Plasmodium falciparum, P. vivax, P. ovale, and P. malariae, four different types of malaria parasites. Additionally, P. knowlesi, a kind of malaria that infects macaques naturally in Southeast Asia, infects people as well, resulting in malaria that is transferred from animal to human ("zoonotic" malaria). The kind of malaria known as P. falciparum is the most likely to cause severe infections and, if untreated, may be fatal.
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