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One event that caused the Human Population in Europe to be reduced by about 1/3 is called the "Bubonic Plague" or Black Death.
The Bubonic Plague, also known as the Black Death lasted between 1346 to 1353.
Bubonic plague is an infection caused by the bacteria Yersinia pestis (Y. pestis), which is spread mostly by fleas on rats and other animals.
Humans who are bitten by fleas are at risk of contracting plague. It is an example of a disease that may be transmitted between animals and humans (a zoonotic disease).
Cats, in particular, are susceptible to plague and can become infected by eating diseased rodents. These cats can transmit plague-infected droplets to their owners or veterinarians who treat them.
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