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using the definition of multiplication between two fractions
[tex]\frac{a}{b}\times\frac{c}{d}=\frac{a\cdot c}{b\cdot d}[/tex]we obtain,
[tex]\frac{5}{3}\times-\frac{3}{4}=-\frac{5\cdot3}{3\cdot4}=-\frac{5}{4}[/tex]