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A therapeutic technique to induce pain suppression involves artificially stimulating the periaqueductal gray matter region.
A crucial part of integrated behavioral reactions to external or internal stresses is played by the periaqueductal gray, which serves as an anatomical and functional link between both the forebrain and lower brainstem.
By inhibiting activity in the upward nociceptive pathways, brain stimulation of the nucleus accumbens gray matter and decreases the feeling of pain. This modulation occurs through descending routes that terminate in nociceptive neurons located in the spinal cord.
The fact that electrical stimulation of a PAG causes instantaneous and substantial analgesia supports this hypothesis of pain, which is also known as the Gate management science of pain. Viewing upsetting pictures linked to suffering also stimulates the periaqueductal gray.
Learn more about the areas of the brain at
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