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NADH/NAD+ ratio would lead to a decrease in the rate of entrance of acetyl coa into the citric acid cycle.
The Krebs cycle, often referred to as the TCA cycle (tricarboxylic acid cycle), and the citric acid cycle (CAC) are chemical processes that release stored energy through the oxidation of acetyl-CoA obtained from carbs, lipids, and proteins. Organisms that respire (as opposed to organisms that ferment) use the Krebs cycle to produce energy, either through anaerobic or aerobic respiration. The cycle additio0nally supplies the reducing agent NADH and precursors of a few amino a.cids that are needed in a variety of other processes. It may have developed abiogenically and was one of the earliest components of metabolism given its prominent role in numerous metabolic processes. [3] [4] Although it is advertised as a "cycle," metabolites need not adhere to it.
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