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Regardless of whether we are in a situation subject to the population being in HWE or not, the genotype frequencies can be used to calculate the allele frequencies.
What is The Hardy-Weinberg Equation (HWE)?
The Hardy-Weinberg equation states that the frequency at which a specific genotype occurs can be expressed as a ratio of the genotype in question to the total number of alleles in the population.
Algebraically, the equation is expressed as:
p² + 2pq + q² =1
The terms of this equation are defined as follows:
p = the frequency of the dominant allele in a population
q = the frequency of the recessive allele in a population
2pq = the frequency of the heterozygous dominant genotype
p² = the frequency of homozygous dominant genotype
q² = the frequency of homozygous recessive genotype
Because the set of all alleles in the population is made up of one part dominant alleles and one part recessive alleles, the sum of p and q will always equal 1.
For more information about Hardy-Weinberg Equilibrium (HWE) refer to the link:
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