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the movement of glucose into or out of the hepatocyte depends on the hormone-mediated availability of glut-2 transporters. specifically, glut-2 is inserted into the plasma membrane, or removed from it, depending on the presence, or absence, of insulin. T/F

Sagot :

The availability of glut-2 transporters, which is regulated by hormones, determines whether glucose moves into or out of the hepatocyte. In particular, depending on whether or not insulin is present, glut-2 is either inserted into or ejected from the plasma membrane.

Why are hepatocytes a good fit for GLUT2?

Hepatocyte-based GLUT2 functions in both directions (Navale and Paranjape, 2016). It facilitates the absorption of glucose for glycolysis and glycogenesis by hepatocytes. In the course of gluconeogenesis, GLUT 2 controls how much glucose is released from liver cells into the bloodstream.

What do GLUT4 and GLUT2 mean?

Important components for typical carbohydrate metabolism include the glucose-transporter gene products from the liver/islets (GLUT2) and muscle/adipose tissue (GLUT4), which are membrane proteins that allow glucose uptake into cells.

To know more about GLUT4 and GLUT2 visit:-

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