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Ketamine club drug is structurally similar to GABA, and B . I, II, and IV is the correct answer.
According to accumulating research, ketamine induces antidepressant effects by enhancing neuroplasticity, which is sparked by a glutamate surge and GABA regulation. Immediately after ketamine treatment during dissociation, alterations to brain glutamate and GABA are visible via magnetic resonance spectroscopic imaging (MRSI). Few studies, however, evaluate subacute alterations in the initial hours after administration, when ketamine's antidepressant effects start to manifest. Additionally, during this period, ketamine metabolites thought to be responsible for its antidepressant effects emerge. In order to better understand subacute alterations in seven brain regions crucial to the pathogenesis and therapy of depression, this study looked at changes in cerebral Glx (glutamate + glutamine), GABA, and their ratio.
Learn more about ketamine by using this link:
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