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The evidence Watson and Crick had access to (and also utilised) in 1953 was X-ray diffraction data and base ratio data.
The first X-ray photograph of DNA was made in 1952, and Watson and Crick used it to determine the molecular structure of the substance. It was developed by Rosalind Benjamin using an approach called X-ray crystallography and showed the DNA molecule's helical structure. According to Watson and Crick's theory, nitrogenous bases on opposing DNA strands form hydrogen bonds that hold the two strands of the double helix together. Each pair of bases forms a flat "rung" on the ladder-like structure of the DNA molecule. Base pairs don't only consist of any arrangement of bases. DNA's three-dimensional double helix structure, which James Watson and Francis Crick accurately deduced. Hydrogen bonds keep complementary bases together as a pair.
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