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The four primary classes of psychoactive drugs—depressants, stimulants, opioids, and hallucinogens—list three ways in which these compounds might affect brain neurotransmission.
This study examines how the brain's neurotransmitters interact with four psychoactive drugs—MDMA (Ecstasy), cocaine, methamphetamine, and LSD—in order to see whether any connections can be drawn between these substances and psychosis.
Other substances, like cocaine or amphetamine, can disrupt transporters, causing the neurons to produce unusually high levels of natural neurotransmitters or preventing the brain chemicals' regular recycling. In addition, this increases or obstructs the usual neuronal transmission.
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