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to cause cancer, proto-oncogenes require allele(s) to be mutated and are therefore considered .

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To cause cancer, proto-oncogenes require allele(s) to be mutated and are therefore considered dominant (or) recessive.

What causes the mutation of proto-oncogenes?

  • Numerous genetic processes, such as transduction, insertional mutagenesis, amplification, point mutations, and chromosomal translocations, can activate proto-oncogenes. Each time a genetic anomaly occurs, a proto-oncogene that was previously bound by regulatory restrictions becomes loose.
  • A proto-mutation oncogene's causes it to become permanently activated. The gene then begins producing an excessive amount of the proteins that regulate cell development. Uncontrollable cell growth happens. Because the cell acquires a new function, this mutation is known as a gain-of-function mutation.
  • Proto-oncogenes are dominant (or) recessive because they need one (or) two allele(s) to be mutated in order to produce cancer.

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