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Looking at the pedigree it can be specified that alkaptonuria is caused by a recessive allele because the unaffected parents (Ann and Michael) give rise to an affected child (Carla).
Pedigree is a flow chart system used to describe the family tree of an individual. It can also help in finding the ancestral roots or the origin of any trait or disease in the family. It consists of lines and some shapes that have their specific meanings.
Alkaptonuria is a recessive disease caused due to defect in the HGD gene. The result of the defect is that the body becomes unable to break down amino acids like tyrosine and phenylalanine. This results in the production of homogentisic acid in the tissues and skin.
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The pedigree below traces the inheritance of alkaptonuria, a biochemical disorder. Affected individuals, indicated hereby the colored circles and squares, are unable to metabolize a substance called alkapton, which colors the urine and stains body tissues. Does alkaptonuria appear to be caused by a dominant allele or a recessive allele?
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