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The solubility of potassium nitrate in 20 C water in gram 100 ml is 31.6g/100mL.
Since medication compounds must be dissolved before they can be taken, solubility is a crucial consideration. In the Biopharmaceutical Classification System (BCS), solubility and rate of dissolution play a critical role since, according to Fick's first law, permeability and solubility together determine how quickly medications are absorbed across the GI tract. Without taking solubility into account, results from in vitro tests like those for HTS activity or membrane permeability may not be correctly evaluated. As it frequently fails to derive a correlation between dose and in vivo efficacy, dosing poorly soluble drugs in pharmacological animal research is extremely dangerous.
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