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The patient is admitted with an overdose of phenobarbital. Assessing vital signs, prescribed action would be of the highest priority.
Phenobarbital is a medicine used to treat epilepsy (fits), anxiety and insomnia. It belongs to a class of drugs called barbiturates. A phenobarbital overdose occurs when a person intentionally or accidentally takes too much of this drug. Barbiturates are addictive, producing physical dependence and a life-threatening withdrawal syndrome. Patients with phenobarbital overdose who are handle only with supportive care may remain in a coma for several days due to the long elimination half-life of phenobarbital. We treated two patients with phenobarbital overdoses with nasogastric administration of multiple doses of activated charcoal. This safe therapy significantly shortened both the elimination half-life of phenobarbital and the duration of coma in these patients.
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