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Which of the following mechanisms contributes to the progression of chronic kidney disease?

A. Overactivity of the renin-angiotensin-aldosterone system


Sagot :

Final answer:

The renin-angiotensin-aldosterone system is vital for regulating blood pressure and volume by acting through various steps to produce angiotensin II.


Explanation:

The renin-angiotensin-aldosterone system acts through several steps to produce angiotensin II, which acts to stabilize blood pressure and volume. The kidneys control blood pressure and volume directly, with renin converting angiotensinogen to angiotensin I, and ACE converting angiotensin I to angiotensin II. Angiotensin II raises blood pressure by constricting blood vessels and triggers the release of aldosterone from the adrenal cortex.


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