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THC is psychoactive while CBD is non-psychoactive, interacting with cannabinoid receptors differently.
THC (A-tetrahydrocannabinol) is psychoactive, causing effects on mental activity, pain, and appetite by binding to CB1 and CB2 receptors. In contrast, CBD (cannabidiol) is non-psychoactive and does not produce euphoric characteristics like THC. Both THC and CBD interact with the body's cannabinoid receptors in different ways.
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