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Final answer:
The experiment failed in the primary principle of Replication, leading to loss of credibility and resignation. Without successful replication, scientific claims cannot be substantiated.
Explanation:
The primary principle of experimental design that Pons and Fleischmann's experiment failed was Replication. Despite their initial claim of achieving cold fusion, the lack of consistent results when other scientists attempted to replicate their experiment led to the loss of credibility and subsequent resignation in disgrace.
Replication in scientific experiments involves repeating the experimental procedure to ensure the validity and reliability of the results. In the case of cold fusion, the failure to replicate the initial findings raised doubts about the legitimacy of the discovery.
Without successful replication, scientific claims cannot be substantiated, leading to skepticism and ultimately, discrediting of the original experimenters' work.
Learn more about Principle of Replication in Experimental Design here:
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