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Elderly adults, infants, and different age groups in clinical trials show varied sensitivity to medications due to factors like slowed drug metabolism and developing physiology.
Elderly adults are more sensitive to medications due to factors such as slowed drug metabolism, increased risk of drug-drug interactions, and the prevalence of multiple prescriptions. This population is at a higher risk of adverse effects like falls and reduced bone density from medications.
Infants also exhibit increased sensitivity to medications due to factors such as their developing physiology and variations in drug metabolism, making them more susceptible to adverse reactions or overdosing.
In clinical trials, specific attention is now being given to different populations like older patients, children, and adolescents to assess the safety and effectiveness of medications based on age, gender, and race.
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