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Sagot :
Final answer:
Sulfonamides act as antimetabolites by blocking the synthesis of dihydrofolic acid in bacteria, which hinders folic acid production crucial for nucleic acid synthesis.
Explanation:
Sulfonamides are antimetabolites that competitively inhibit the synthesis of dihydrofolic acid by blocking the enzyme sulfihydropteroate synthase in bacteria. This inhibition disrupts the production of folic acid, essential for nucleic acid synthesis, resulting in bacteriostatic effects.
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