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How does the leading strand differ from the lagging strand in DNA replication?

A. The leading strand contains DNA bases, the lagging strand contains RNA bases.
B. The leading strand builds protein, the lagging strand builds RNA.
C. The leading strand contains only introns, the lagging strand contains only exons.
D. The leading strand is built as one continuous piece, the lagging strand is not.

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Final answer:

The leading strand is synthesized continuously, while the lagging strand is synthesized in short fragments known as Okazaki fragments with the need for multiple primers.


Explanation:

The leading strand is synthesized continuously from a single primer by DNA polymerase, while the lagging strand is synthesized discontinuously in short fragments called Okazaki fragments, each requiring its own primer. The RNA primers are removed and replaced with DNA nucleotides, and DNA ligase seals the gaps between these fragments.


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