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The body's first line of defense includes mechanical and chemical barriers like saliva and inflammation.
The body's first line of defense consists of three different types of barriers that keep most pathogens out of body tissues. Mechanical barriers like the skin and mucous membranes physically block pathogens. Chemical barriers, such as enzymes in saliva and other fluids, kill pathogens on body surfaces. When pathogens breach these barriers, inflammation occurs, creating a physical barrier against infection and promoting tissue repair.
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