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Which of the following is true regarding PD-L1 expression?

A. PD-L1 expression is continuously variable and dynamic.
B. PD-L1 expression is static in tumor cells.
C. PD-L1 expression is only reliably measured by using next-generation sequencing.
D. PD-L1 expression is an ineffective biomarker at predicting response to immunotherapy.

Sagot :

GinnyAnsweridn

Final answer:

PD-L1 expression in cancer cells is dynamic and affects immune response, making it a crucial factor in cancer progression.


Explanation:

PD-L1 expression is continuously variable and dynamic, especially in cancer cells. It plays a crucial role in immune evasion by binding to the PD-1 protein on T-cells, thus allowing cancer cells to evade immune attack. The disruption of PD-1 and PD-L1 interaction by checkpoint inhibitors can enhance T-cell attack on cancer cells.


Learn more about gene expression pattern and cancer here:

https://brainly.com/question/38162337


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