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Sagot :
Final answer:
Horses had the most significant impact on Native American cultures in the Columbian Exchange.
Explanation:
Horse had the greatest effect on Native American cultures in the Columbian Exchange. The introduction of horses by the Spanish in the 1500s transformed the way of life for many Native American tribes, such as the Plains and Plateau Native Americans. Horses revolutionized transportation, hunting, warfare, and trade among Native American societies.
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