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What happens on a cellular level during a organ rejection? Simplified.

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The ability of recipient T cells to recognize donor-derived antigens, called allorecognition, initiates allograft rejection. Once recipient T cells become activated, they undergo clonal expansion, differentiate into effector cells, and migrate into the graft where they promote tissue destruction.
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Organ rejection takes place when your body is subjected to a new organ which is a foreign object and attacks it.

What do you mean by Graft rejection?

Graft rejection may be defined as a process in which a transplant recipient's immune system attacks the transplanted organ or tissue.

Xenograft shows high rejection. This is because it involves the transplantation between genetically distinct members of different species.

The process of organ rejection is initiated by T cells which perform the role of the recognization of a transplanted organ.

If these T cells are activated, it may lead to organ rejection by undergoing clonal expansion, and differentiation of the effector cells, which together lead to the obliteration of the tissues.

Therefore, organ rejection takes place when your body is subjected to a new organ which is a foreign object, and attacks it.

To learn more about Organ rejection, refer to the link:

https://brainly.com/question/1313114

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