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If an individual has a mutation that prevents degradation of Rec8, then this would most likely prevent correct segregation during meiosis II.
In genetics, the term disjunction make reference to the separation of homo-logous chromosomes during meiosis.
Non-disjunction leads to the generation of unbalanced gametes with more chromosomes than normal.
Rec8 is a protein involved in the separation (disjunction) of the homo-logous chromosomes during cell division.
Learn more about chromosome disjunction here:
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