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Water channels in cell membranes formed by aquaporins are a result of ADH signaling in the kidneys.
What is ADH signaling in kidneys?
- The main hormone in charge of maintaining tonicity homeostasis is ADH.
- Its release is most strongly triggered in hyperosmolar conditions.
- The neurons of the hypothalamus store ADH.
- These neurons have osmoreceptors that respond to variations in blood osmolarity as little as two mOsm/L and are incredibly receptive to them .
- As a result, ADH is secreted in response to modest increases in osmolarity.
- Then, ADH works largely in the kidneys to boost water absorption, bringing the osmolarity back to normal.
What are Aquaporins?
Aquaporins, also known as water channels, are channel proteins that produce pores in the membrane of living cells, primarily aiding the passage of water between cells. They are part of a wider family of important intrinsic proteins.
Learn more about osmoregulation in kidneys here:
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