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Erythromycin inhibits the translation in Prokaryotes (Bacteria) but does not affect the Eukaryotes.
Near the location where chloramphenicol binds to the 50S ribosomal subunit of bacteria, erythromycin binds. It stops peptidyl-tRNA from moving from site A to site P in the ribosome.
Erythromycin- A topical macrolide antibiotic having broad-spectrum antibacterial action. The 50S component of the bacterial ribosome is reversibly bound by erythromycin, which diffuses across the membrane of the bacterial cell results in bacterial protein inhibition.
Translation- The method by which a cell uses the genetic data conveyed in messenger RNA to produce proteins (mRNA). The information included in the mRNA, which is created by replicating DNA, instructs the cell on how to assemble proteins from amino acids.
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