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Which of the following is true regarding immune-related adverse events associated with the use of immune checkpoint inhibitor therapy?

A. These reactions are highly correlated with the second dose of checkpoint inhibitor therapy.
B. These reactions may have delayed onset and may be inflammatory or autoimmune in nature.
C. Corticosteroids should only be given for grade 3 toxicities.
D. These reactions are less likely to occur when checkpoint inhibitor therapy is combined with targeted therapy.


Sagot :

Final answer:

Immune-related adverse events with immune checkpoint inhibitors can have delayed onset and may be inflammatory/autoimmune. Corticosteroids may be necessary for grade 3 toxicities, and the reactions are not less likely with combined therapy.


Explanation:

Regarding immune-related adverse events associated with the use of immune checkpoint inhibitor therapy:

  1. These reactions may have delayed onset and may be inflammatory or autoimmune in nature.
  2. Corticosteroids may need to be given for grade 3 or higher toxicities.
  3. These reactions are not less likely to occur when checkpoint inhibitor therapy is combined with targeted therapy.

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